Sterile setup for knee injection preparation

Monovisc Injection

Name: Monovisc Injection
Creator: Prof Paul Lee

From £1,200

Guide price only. Final cost is confirmed after assessment.

Monovisc Injection represents a significant advancement in treating osteoarthritis knee pain. This innovative, single-shot hyaluronic acid treatment at London Cartilage Clinic offers patients a simple yet effective solution for managing knee pain associated with osteoarthritis. With its unique formulation and proven effectiveness, Monovisc Injection stands out as a preferred choice for those seeking relief from joint discomfort.

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Reviewed byProf Paul Lee MBBch, FRCS (Tr & Orth), PhDLast reviewed 1 May 2026

Physiotherapist examining patient's knee on couch

Understanding Monovisc
single-injection HA therapy

Monovisc is a highly purified hyaluronic acid viscosupplement designed to mimic the knee’s natural lubrication and cushioning properties.

Supports smoother motion in osteoarthritic joints.
May reduce pain and stiffness with a single treatment session.
Biocompatible formulation with broad clinical use in knee OA care.

It is commonly considered for patients who have persistent symptoms despite first-line conservative management.

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Benefits of Monovisc
at London Cartilage Clinic

Monovisc offers a convenient, single-injection pathway for knee osteoarthritis symptom control with minimal disruption to routine life.

Fewer clinic visits compared with multi-injection regimens.
Potential for medium-term pain and mobility improvement.
Can be repeated at clinically appropriate intervals.

At London Cartilage Clinic, ultrasound-guided technique and specialist follow-up are used to optimise treatment precision and track your functional response.

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Blue-gloved hands preparing injection syringe

Frequently Asked Questions

How long does Monovisc Injection take to work?

The onset of pain relief with Monovisc Injection varies, but many patients report a noticeable improvement in knee pain within a few weeks after the injection.

Is Monovisc Injection suitable for everyone?

Monovisc Injection is ideal for patients with knee osteoarthritis who haven’t found relief with traditional treatments. However, it’s important to consult with our specialists to determine if it’s the right option for you.

Are there any side effects of Monovisc Injection?

Monovisc Injection is generally well-tolerated, but like any medical treatment, it may have side effects. Our clinic ensures a thorough assessment to minimize any risks.

How is Monovisc administered?

A trained specialist uses a single injection to administer Monovisc. This is known as viscosupplementation. During the procedure, the patient will either be lying down or sitting, and a local anaesthetic may be used. The injected area is cleaned and bandaged after the Monovisc has been administered.

How does Monovisc help with osteoarthritis knee pain?

The Monovisc injection contains ultra-pure hyaluronic acid, which can be found in the synovial fluid of the knee joint. This gel-like substance lubricates the joint, helping prevent damage and discomfort that might lead to pain. By allowing the bones of the joint to move more freely, Monovisc injections also help delay the onset of osteoarthritis.

How long should I wait between injections?

Most patients will be able to go for a repeat procedure after six months. However, this may not be true depending on your situation. If your osteoarthritis is deemed to be too advanced, then your surgeon may advise knee replacement surgery.

Still have more specific concerns?

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London Cartilage Clinic